Research translating basic science discoveries into clinical applications
Approximately one in seven adults over the age of 65 experience moderate to severe cognitive impairments, including problems with memory. These impairments adversely impact the ability of the elderly to remain functionally independent, and also interfere with their health status and quality of life.
With healthier lifestyles and advances in medical science, the human lifespan has almost doubled in the past century. These improvements in somatic health, however, are currently outpacing our ability to maintain cognitive functioning into advanced ages.
Research FOCUS AREAS
This area focuses on understanding and improving memory and executive functioning, which are cognitive domains that are known to decline with advanced age.
This area focuses on analyzing the mechanisms underlying cognitive decline, and identifying key genetic and modifiable lifestyle factors that predict decline and increase the probability of developing comorbid age-related diseases.
This area focuses on visualizing and analyzing brain activity in conjunction with cognitive processing and behavior.
This area focuses on preclinical and clinical assessment of potential therapeutics for preventing, halting or reversing cognitive decline.
Facilities and Resources
The CAM Center operates within UF’s Evelyn F. and William L. McKnight Brain Institute (MBI). On the ground floor of the MBI, CAM Center investigators conduct clinical research studies in newly renovated high-tech labs that include testing rooms for clinical and cognitive assessments, an electrophysiology suite, a transcranial magnetic stimulation lab and new waiting areas for study participants next door to a new Siemens 3T MRI/S state-of-the-art scanner and phlebotomy lab. The MBI further houses CAM Center investigators focused on preclinical discovery research in over 5,000 square feet of dedicated laboratory space, containing the latest equipment for monitoring and interrogating the aged brain.
Research Snapshots pair an impactful image from work in a researcher’s laboratory, with a brief description of what the image represents and how it has impacted the researcher’s field of study.
See recent papers published by CAM Center researchers.