Barry Setlow

Barry Setlow, Ph.D.

Professor

Department: MD-PSYCHIATRY
Business Phone: (352) 294-5203
Business Email: setlow@ufl.edu

About Barry Setlow

Barry Setlow received his PhD in 1998 from the University of California, Irvine, where he worked with Jim McGaugh on amygdala-striatal systems involved in consolidation of different forms of learning and memory. He went on to post-doctoral training with Michela Gallagher at Johns Hopkins University, where he continued work on the role of amygdala-striatal systems in different forms of learning, using both behavioral and single-unit electrophysiological recording techniques. From there he moved to a position as an assistant professor at Texas A&M University, where his research focussed on the effects of both acute and chronic exposure to drugs of abuse on cognition, with a particular focus on decision-making. Dr. Setlow joined the Department of Psychiatry in 2010, where he is continuing his research on interactions between drug abuse and decision-making, as well as collaborating with other UF investigators on animal models of age-related cognitive decline.

Accomplishments

UF Research Foundation Professorship
2018-2021 · University of Florida
Fellow
2017-Current · University of California, Irvine Center for the Neurobiology of Learning and Memory
UF Term Professorship
2017-2020 · University of Florida
Exemplary Teacher
2016 · University of Florida, College of Medicine
Faculty of Neuroscience Leadership and Service Award
2010 · Texas A&M University
Young Investigator Travel Award
2008 · American College of Neuropsychopharmacology
J. L. McGaugh Award for Excellence in Graduate Research
1998 · Department of Psychobiology, University of California, Irvine
Ralph Waldo Gerard Prize in the History of Neuroscience
1996 · University of California, Irvine

Teaching Profile

Courses Taught
2014-2022
GMS6780 Addiction: Neuroscience and Trends
2020-2021
GMS6757 Introduction to Alzheimer’s Disease and Related Dementias: Clinical and Mechanistic Principles
2013-2015,2017-2021,2021
GMS6029 Brain Journal Club
2017-2021
GMS6705 Functional Human Neuroanatomy
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS7979 Advanced Research
2018
GMS6022 Prin Neuroscience 2
2015
GMS7794 Neuroscience Seminar
2022
GMS6090 Research in Medical Sciences

Research Profile

Research Interests:

– behavioral, pharmacological, and neural basis of decision-making

– acute and chronic effects of drugs of abuse (stimulants, cannabinoids, opioids) on cognition and motivation

– neural mechanisms of age-related cognitive decline

Open Researcher and Contributor ID (ORCID)

0000–000-1-91-33-9-445

Publications

2022
Chronic cocaine causes age-dependent increases in risky choice in both males and females.
Behavioral Neuroscience. 136(3):243-263 [DOI] 10.1037/bne0000509.
2022
GABAB receptors in prelimbic cortex and basolateral amygdala differentially influence intertemporal decision making and decline with age.
Neuropharmacology. 209 [DOI] 10.1016/j.neuropharm.2022.109001. [PMID] 35189132.
2022
Treatment initiation and utilization patterns of pharmacotherapies for early-onset idiopathic restless legs syndrome
Sleep Medicine. 96:70-78 [DOI] 10.1016/j.sleep.2022.05.003.
2021
Acute vagus nerve stimulation enhances reversal learning in rats.
Neurobiology of learning and memory. 184 [DOI] 10.1016/j.nlm.2021.107498. [PMID] 34332068.
2021
Cocaine and Marijuana Polysubstance Use and Cocaine Use Disorder: Investigating Mediated Effects through Patterns of Cocaine Use.
Journal of dual diagnosis. 17(1):23-33 [DOI] 10.1080/15504263.2020.1849887. [PMID] 33300839.
2021
Effects of a high-fat diet on impulsive choice in rats.
Physiology & behavior. 229 [DOI] 10.1016/j.physbeh.2020.113260. [PMID] 33227243.
2021
Effects of repeated adolescent exposure to cannabis smoke on cognitive outcomes in adulthood
Journal of Psychopharmacology. 35(7):848-863 [DOI] 10.1177/0269881120965931. [PMID] 33295231.
2021
Neuron-specific cilia loss differentially alters locomotor responses to amphetamine in mice.
Journal of neuroscience research. 99(3):827-842 [DOI] 10.1002/jnr.24755. [PMID] 33175436.
2021
Regulation of risky decision making by gonadal hormones in males and females
Neuropsychopharmacology. 46(3):603-613 [DOI] 10.1038/s41386-020-00827-0. [PMID] 32919406.
2020
Author response: Testicular hormones mediate robust sex differences in impulsive choice in rats
. [DOI] 10.7554/elife.58604.sa2.
2020
Distinct relationships between risky decision making and cocaine self-administration under short- and long-access conditions.
Progress in neuro-psychopharmacology & biological psychiatry. 98 [DOI] 10.1016/j.pnpbp.2019.109791. [PMID] 31676462.
2020
Testicular hormones mediate robust sex differences in impulsive choice in rats
eLife. 9 [DOI] 10.7554/elife.58604.
2020
Using rodent models to understand interactions between gambling and substance use.
Current opinion in behavioral sciences. 31:37-41 [DOI] 10.1016/j.cobeha.2019.10.012. [PMID] 33102640.
2019
Author response: Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats
. [DOI] 10.7554/elife.46174.024.
2019
Deconstructing value-based decision making via temporally selective manipulation of neural activity: Insights from rodent models.
Cognitive, affective & behavioral neuroscience. 19(3):459-476 [DOI] 10.3758/s13415-018-00649-0. [PMID] 30341621.
2019
Effects in rats of adolescent exposure to cannabis smoke or THC on emotional behavior and cognitive function in adulthood.
Psychopharmacology. 236(9):2773-2784 [DOI] 10.1007/s00213-019-05255-7. [PMID] 31044291.
2019
Enhancing effects of acute exposure to cannabis smoke on working memory performance.
Neurobiology of learning and memory. 157:151-162 [DOI] 10.1016/j.nlm.2018.12.001. [PMID] 30521850.
2019
Intergenerational Effects of Sevoflurane in Young Adult Rats.
Anesthesiology. 131(5):1092-1109 [DOI] 10.1097/ALN.0000000000002920. [PMID] 31517640.
2019
Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats
eLife. 8 [DOI] 10.7554/elife.46174.
2019
Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats.
Cannabis and cannabinoid research. 4(4):240-254 [DOI] 10.1089/can.2019.0049. [PMID] 32042924.
2019
Recent Updates in Modeling Risky Decision Making in Rodents.
Methods in molecular biology (Clifton, N.J.). 2011:79-92 [DOI] 10.1007/978-1-4939-9554-7_5. [PMID] 31273694.
2019
Risky decision-making is associated with impulsive action and sensitivity to first-time nicotine exposure.
Behavioural brain research. 359:579-588 [DOI] 10.1016/j.bbr.2018.10.008. [PMID] 30296531.
2019
The perirhinal cortex supports spatial intertemporal choice stability.
Neurobiology of learning and memory. 162:36-46 [DOI] 10.1016/j.nlm.2019.05.002. [PMID] 31125611.
2018
Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory.
eNeuro. 5(3) [DOI] 10.1523/ENEURO.0164-18.2018. [PMID] 29971246.
2018
Contributions of medial prefrontal cortex to decision making involving risk of punishment.
Neuropharmacology. 139:205-216 [DOI] 10.1016/j.neuropharm.2018.07.018. [PMID] 30009836.
2018
Effects of combined brief etomidate anesthesia and postnatal stress on amygdala expression of Cl- cotransporters and corticotropin-releasing hormone and alcohol intake in adult rats.
Neuroscience letters. 685:83-89 [DOI] 10.1016/j.neulet.2018.08.019. [PMID] 30125644.
2018
Functional Connectivity of Chronic Cocaine Use Reveals Progressive Neuroadaptations in Neocortical, Striatal, and Limbic Networks.
eNeuro. 5(4) [DOI] 10.1523/ENEURO.0081-18.2018. [PMID] 30073194.
2018
Functional connectivity, behavioral and dopaminergic alterations 24 hours following acute exposure to synthetic bath salt drug methylenedioxypyrovalerone.
Neuropharmacology. 137:178-193 [DOI] 10.1016/j.neuropharm.2018.04.031. [PMID] 29729891.
2018
MeCP2 Expression in a Rat Model of Risky Decision Making.
Neuroscience. 369:212-221 [DOI] 10.1016/j.neuroscience.2017.11.016. [PMID] 29155278.
2018
Monoaminergic modulation of decision-making under risk of punishment in a rat model.
Behavioural pharmacology. 29(8):745-761 [DOI] 10.1097/FBP.0000000000000448. [PMID] 30394882.
2018
Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant.
Journal of pharmaceutical and biomedical analysis. 160:119-125 [DOI] 10.1016/j.jpba.2018.07.004. [PMID] 30077950.
2018
Stress-induced corticosterone secretion covaries with working memory in aging.
Neurobiology of aging. 71:156-160 [DOI] 10.1016/j.neurobiolaging.2018.07.015. [PMID] 30144648.
2018
The importance of considering polysubstance use: lessons from cocaine research.
Drug and alcohol dependence. 192:16-28 [DOI] 10.1016/j.drugalcdep.2018.07.025. [PMID] 30195242.
2017
Adolescent Cannabinoid Use and Cognition; Unexpected Results from a Rat Model of Cannabinoid Self-Administration.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 42(5):983-984 [DOI] 10.1038/npp.2016.212. [PMID] 27654216.
2017
Cocaine and intertemporal decision making.
. 375-382
2017
Decline of prefrontal cortical-mediated executive functions but attenuated delay discounting in aged Fischer 344 × brown Norway hybrid rats.
Neurobiology of aging. 60:141-152 [DOI] 10.1016/j.neurobiolaging.2017.08.025. [PMID] 28946018.
2017
Effects of nucleus accumbens amphetamine administration on performance in a delay discounting task.
Behavioural brain research. 321:130-136 [DOI] 10.1016/j.bbr.2017.01.001. [PMID] 28057530.
2017
Interaction between age and perceptual similarity in olfactory discrimination learning in F344 rats: relationships with spatial learning.
Neurobiology of aging. 53:122-137 [DOI] 10.1016/j.neurobiolaging.2017.01.023. [PMID] 28259065.
2017
Optogenetic Inhibition Reveals Distinct Roles for Basolateral Amygdala Activity at Discrete Time Points during Risky Decision Making.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(48):11537-11548 [DOI] 10.1523/JNEUROSCI.2344-17.2017. [PMID] 29079687.
2017
Prefrontal cortical GABAergic signaling and impaired behavioral flexibility in aged F344 rats.
Neuroscience. 345:274-286 [DOI] 10.1016/j.neuroscience.2016.02.014. [PMID] 26873002.
2017
Sex differences in animal models of decision making.
Journal of neuroscience research. 95(1-2):260-269 [DOI] 10.1002/jnr.23810. [PMID] 27870448.
2016
Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction.
Molecular genetics & genomic medicine. 4(3):322-43 [DOI] 10.1002/mgg3.207. [PMID] 27247960.
2016
Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats.
PloS one. 11(4) [DOI] 10.1371/journal.pone.0153327. [PMID] 27065006.
2016
Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis.
Hippocampus. 26(4):455-71 [DOI] 10.1002/hipo.22535. [PMID] 26418152.
2016
Effects of acute administration of the GABA(B) receptor agonist baclofen on behavioral flexibility in rats.
Psychopharmacology. 233(14):2787-97 [DOI] 10.1007/s00213-016-4321-y. [PMID] 27256354.
2016
NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(50):12537-12548 [PMID] 27807032.
2016
Sex differences in a rat model of risky decision making.
Behavioral neuroscience. 130(1):50-61 [DOI] 10.1037/bne0000111. [PMID] 26653713.
2016
The Psychoactive Designer Drug and Bath Salt Constituent MDPV Causes Widespread Disruption of Brain Functional Connectivity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 41(9):2352-65 [DOI] 10.1038/npp.2016.40. [PMID] 26997298.
2015
Affective and cognitive mechanisms of risky decision making.
Neurobiology of learning and memory. 117:60-70 [DOI] 10.1016/j.nlm.2014.03.002. [PMID] 24642448.
2015
Characterizing olfactory binary mixture interactions in Fischer 344 rats using behavioral reaction times.
Chemical senses. 40(5):325-34 [DOI] 10.1093/chemse/bjv014. [PMID] 25877697.
2015
Choice impulsivity: Definitions, measurement issues, and clinical implications.
Personality disorders. 6(2):182-98 [DOI] 10.1037/per0000099. [PMID] 25867841.
2015
Dissociable roles for the basolateral amygdala and orbitofrontal cortex in decision-making under risk of punishment.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(4):1368-79 [DOI] 10.1523/JNEUROSCI.3586-14.2015. [PMID] 25632115.
2015
Modeling Cost–Benefit Decision Making in Aged Rodents
Aging and Decision Making. 17-40 [DOI] 10.1016/B978-0-12-417148-0.00002-9.
2015
Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models.
Neuroscience and biobehavioral reviews. 58:147-67 [DOI] 10.1016/j.neubiorev.2015.04.009. [PMID] 26072028.
2014
Adolescent risk taking, cocaine self-administration, and striatal dopamine signaling.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 39(4):955-62 [DOI] 10.1038/npp.2013.295. [PMID] 24145852.
2014
Adolescent risk taking, cocaine self-administration, and striatal dopamine signaling.
. 39(4)
2014
Behavioral Alterations and Dependence Following Acute and Chronic Exposure To Cannabis Smoke
Neuropsychopharmacology. 39(1):S599-S600
2014
Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats.
Chemical senses. 39(4):323-31 [DOI] 10.1093/chemse/bju001. [PMID] 24488965.
2014
Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats.
Chemical Senses. 39(4)
2014
Food consumption and weight gain after cessation of chronic amphetamine administration.
Appetite. 78:76-80 [DOI] 10.1016/j.appet.2014.03.013. [PMID] 24667154.
2014
Food consumption and weight gain after cessation of chronic amphetamine administration.
Appetite. 78:76-80
2014
Impulsivity, risk-taking, and distractibility in rats exhibiting robust conditioned orienting behaviors.
Journal of the experimental analysis of behavior. 102(2):162-78 [DOI] 10.1002/jeab.104. [PMID] 25130520.
2014
Intake-dependent effects of cocaine self-administration on impulsive choice in a delay discounting task.
Behavioral neuroscience. 128(4):419-29 [DOI] 10.1037/a0036742. [PMID] 24841739.
2014
Lesions of the Orbitofrontal Cortex Reduce Risk-Taking in Rats
Neuropsychopharmacology. 39(1)
2014
Prefrontal cortical GABAergic dysfunction contributes to age-related working memory impairment.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(10):3457-66 [DOI] 10.1523/JNEUROSCI.5192-13.2014. [PMID] 24599447.
2014
Subtypes of Prefrontal Cortical Nmda Receptors in Working Memory and Normal Aging
Neuropsychopharmacology. 39(1)
2013
Adolescent Risk Taking, Dopamine, and Cocaine: a Vicious Cycle
Biological Psychiatry. 73:40S-41S
2013
Alpha 4 Beta 2{*}and Alpha 7 Nicotinic Acetylcholine Receptor Binding Predicts Choice Preference in Two Cost Benefit Decision-Making Tasks
Neuroscience. 230:121-131 [DOI] 10.1016/j.neuroscience.2012.10.067. [PMID] 23159316.
2013
Distinct manifestations of executive dysfunction in aged rats.
Neurobiology of aging. 34(9):2164-74 [DOI] 10.1016/j.neurobiolaging.2013.03.019. [PMID] 23601673.
2013
Effects of ventral striatal lesions on first- and second-order appetitive conditioning.
The European journal of neuroscience. 38(4):2589-99 [DOI] 10.1111/ejn.12255. [PMID] 23691939.
2013
Prefrontal cortical-striatal dopamine receptor mRNA expression predicts distinct forms of impulsivity.
The European journal of neuroscience. 37(11):1779-88 [DOI] 10.1111/ejn.12191. [PMID] 23510331.
2012
Altered spatial learning and delay discounting in a rat model of human third trimester binge ethanol exposure.
Behavioural pharmacology. 23(1):54-65 [DOI] 10.1097/FBP.0b013e32834eb07d. [PMID] 22129556.
2012
Effects of acute administration of nicotinic and muscarinic cholinergic agonists and antagonists on performance in different cost-benefit decision making tasks in rats.
Psychopharmacology. 224(4):489-99 [DOI] 10.1007/s00213-012-2777-y. [PMID] 22760484.
2012
Effects of developmental nicotine exposure in rats on decision-making in adulthood.
Behavioural pharmacology. 23(1):34-42 [DOI] 10.1097/FBP.0b013e32834eb04a. [PMID] 22123182.
2012
Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction.
Brain research. 1463:85-92 [DOI] 10.1016/j.brainres.2012.04.053. [PMID] 22575564.
2012
Modeling risky decision making in rodents.
Methods in molecular biology (Clifton, N.J.). 829:165-75 [DOI] 10.1007/978-1-61779-458-2_10. [PMID] 22231813.
2012
Risk, reward, and decision-making in a rodent model of cognitive aging
Frontiers in Neuroscience.
2011
Dopaminergic modulation of risky decision-making.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(48):17460-70 [DOI] 10.1523/JNEUROSCI.3772-11.2011. [PMID] 22131407.
2011
Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making in rats.
Psychopharmacology. 218(4):703-12 [DOI] 10.1007/s00213-011-2363-8. [PMID] 21638222.
2011
Risk, reward, and decision-making in a rodent model of cognitive aging.
Frontiers in neuroscience. 5 [DOI] 10.3389/fnins.2011.00144. [PMID] 22319463.
2010
Good things come to those who wait: attenuated discounting of delayed rewards in aged Fischer 344 rats.
Neurobiology of aging. 31(5):853-62 [DOI] 10.1016/j.neurobiolaging.2008.06.004. [PMID] 18657883.
2010
Self-administered cocaine causes long-lasting increases in impulsive choice in a delay discounting task.
Behavioral neuroscience. 124(4):470-7 [DOI] 10.1037/a0020458. [PMID] 20695646.
2009
An animal model of hypnotic pain attenuation.
Behavioural brain research. 197(1):198-204 [DOI] 10.1016/j.bbr.2008.08.020. [PMID] 18793674.
2009
Balancing risk and reward: a rat model of risky decision making.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 34(10):2208-17 [DOI] 10.1038/npp.2009.48. [PMID] 19440192.
2009
Cocaine self-administration alters the relative effectiveness of multiple memory systems during extinction.
Learning & memory (Cold Spring Harbor, N.Y.). 16(5):296-9 [DOI] 10.1101/lm.1253409. [PMID] 19389915.
2009
Effects of chronic administration of drugs of abuse on impulsive choice (delay discounting) in animal models.
Behavioural pharmacology. 20(5-6):380-9 [DOI] 10.1097/FBP.0b013e3283305eb4. [PMID] 19667970.
2009
Effects of prior amphetamine exposure on approach strategy in appetitive Pavlovian conditioning in rats
. 202(4)
2009
Effects of prior amphetamine exposure on approach strategy in appetitive Pavlovian conditioning in rats.
Psychopharmacology. 202(4):699-709 [DOI] 10.1007/s00213-008-1353-y. [PMID] 18850090.
2009
Georges ungar and memory transfer
. 181-192
2009
Georges ungar and memory transfer
. 181-192
2009
Long-lasting sensitization of reward-directed behavior by amphetamine.
Behavioural brain research. 201(1):74-9 [DOI] 10.1016/j.bbr.2009.01.034. [PMID] 19428619.
2009
Multiple memory systems and extinction: oral cocaine use selectively impairs “cognitive” latent extinction.
Learning & Memory. 16
2009
Spatial reference and working memory across the lifespan of male Fischer 344 rats
Neurobiology of Aging. 30(4)
2008
Long-term effects of prior cocaine exposure on Morris water maze performance.
Neurobiology of learning and memory. 89(2):185-91 [PMID] 17904876.
2008
Sensory recognition versus motor output: dual components in Pavlovian conditioning.
Experimental Brain Research. 185
2008
Timing in the absence of supraspinal input I: variable, but not fixed, spaced stimulation of the sciatic nerve undermines spinally-mediated instrumental learning.
Neuroscience. 155(4):1030-47 [DOI] 10.1016/j.neuroscience.2008.07.003. [PMID] 18674601.
2008
Undoing cocaine’s consequences on behavior and brain.
Proceedings of the National Academy of Sciences of the United States of America. 105(44):16829-30 [DOI] 10.1073/pnas.0809529105. [PMID] 18974216.
2007
Cocaine exposure causes long-term increases in impulsive choice.
Behavioral neuroscience. 121(3):543-9 [PMID] 17592945.
2007
Cognitive impairments in Morris water maze and odor discrimination learning in a subset of aged Fisher 344 rats.
Neurobiology of Aging. 28
2007
Deficits across multiple cognitive domains in a subset of aged Fischer 344 rats.
Neurobiology of aging. 28(6):928-36 [PMID] 16806587.
2006
Encoding changes in orbitofrontal cortex in reversal-impaired aged rats.
Journal of neurophysiology. 95(3):1509-17 [PMID] 16338994.
2006
Post-training amphetamine administration enhances memory consolidation in appetitive Pavlovian conditioning: Implications for drug addiction.
Neurobiology of learning and memory. 86(3):305-10 [PMID] 16750404.
2005
Cocaine makes actions insensitive to outcomes but not extinction: implications for altered orbitofrontal-amygdalar function.
Cerebral cortex (New York, N.Y. : 1991). 15(8):1162-9 [PMID] 15563719.
2005
Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America. 102(30):10718-23 [PMID] 16020527.
2004
Cocaine-experienced rats exhibit learning deficits in a task sensitive to orbitofrontal cortex lesions.
The European journal of neuroscience. 19(7):1997-2002 [PMID] 15078575.
2003
A systems approach to orbitofrontal cortex function: recordings in rat orbitofrontal cortex reveal interactions with different learning systems.
Behavioural brain research. 146(1-2):19-29 [PMID] 14643456.
2003
Different roles for orbitofrontal cortex and basolateral amygdala in a reinforcer devaluation task.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(35):11078-84 [PMID] 14657165.
2003
Encoding predicted outcome and acquired value in orbitofrontal cortex during cue sampling depends upon input from basolateral amygdala.
Neuron. 39(5):855-67 [PMID] 12948451.
2003
Lesions of nucleus accumbens disrupt learning about aversive outcomes.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(30):9833-41 [PMID] 14586012.
2003
Lesions of orbitofrontal cortex and basolateral amygdala complex disrupt acquisition of odor-guided discriminations and reversals.
Learning & memory (Cold Spring Harbor, N.Y.). 10(2):129-40 [PMID] 12663751.
2003
Neural encoding in ventral striatum during olfactory discrimination learning.
Neuron. 38(4):625-36 [PMID] 12765613.
2002
Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating.
The Journal of Neuroscience. 22(19)
2002
Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 22(19):8748-53 [PMID] 12351750.
2002
Disconnection of the basolateral amygdala complex and nucleus accumbens impairs appetitive pavlovian second-order conditioned responses.
Behavioral neuroscience. 116(2):267-75 [PMID] 11996312.
2002
Orbitofrontal lesions in rats impair reversal but not acquisition of go, no-go odor discriminations.
Neuroreport. 13(6):885-90 [PMID] 11997707.
2002
The basolateral complex of the amygdala is necessary for acquisition but not expression of CS motivational value in appetitive Pavlovian second-order conditioning.
The European journal of neuroscience. 15(11):1841-53 [PMID] 12081664.
2001
A novel method for detecting licking behavior during recording of electrophysiological signals from the brain.
Journal of neuroscience methods. 106(2):139-46 [PMID] 11325433.
2001
Basolateral amygdala-nucleus accumbens interactions in mediating glucocorticoid enhancement of memory consolidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(7):2518-25 [PMID] 11264325.
2001
Basolateral amygdala-nucleus accumbens interactions in mediating glucocorticoid enhancement of memory consolidation.
The Journal of Neuroscience. 21(7)
2001
Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(14):5089-98 [PMID] 11438584.
2001
Integrating Orbitofrontal Cortex into Prefrontal Theory: Common Processing Themes across Species and Subdivisions
Learning & Memory. 8(3):134-47 [DOI] 10.1101/lm.39901. [PMID] 11390633.
2000
D2 Dopamine Receptor Blockade Immediately Post-training Enhances Retention in Hidden and Visible Platform Versions of the Water Maze
Learning & Memory. 7(3):187-191 [DOI] 10.1101/lm.7.3.187.
2000
Impaired memory consolidation in rats produced with beta-adrenergic blockade.
Neurobiology of learning and memory. 74(3):259-66 [PMID] 11031131.
2000
Involvement of a basolateral amygdala complex-nucleus accumbens pathway in glucocorticoid-induced modulation of memory consolidation.
The European journal of neuroscience. 12(1):367-75 [PMID] 10651892.
2000
The basolateral amygdala complex is involved with, but is not necessary for, rapid acquisition of Pavlovian ‘fear conditioning’.
The European journal of neuroscience. 12(8):3044-50 [PMID] 10971645.
1999
Differential effects of immediate posttraining sulphide microinfusions into the nucleus accumbens shell and core on Morris water maze retention
. 27(2)
1999
Involvement of the posteroventral caudate-putamen in memory consolidation in the Morris water maze.
Neurobiology of learning and memory. 71(2):240-7 [PMID] 10082643.
1998
Sulpiride infused into the nucleus accumbens posttraining impairs memory of spatial water maze training.
. 112(3)
1998
Sulpiride infused into the nucleus accumbens posttraining impairs memory of spatial water maze training.
Behavioral neuroscience. 112(3):603-10 [DOI] 10.1037/0735-7044.112.3.603. [PMID] 9676976.
1997
Georges ungar and memory transfer
Journal of the History of the Neurosciences. 6(2):181-192 [DOI] 10.1080/09647049709525701.
1997
The nucleus accumbens and learning and memory.
Journal of neuroscience research. 49(5):515-21 [PMID] 9302072.
1996
Multiple memory systems and cortico-striatal anatomy: A new approach
. 13(2)

Grants

Feb 2022 ACTIVE
Role of Dopamine receptor-expressing cortical projection circuits in cognitive flexibility
Role: Co-Investigator
Funding: NATL INST OF HLTH NIMH
Sep 2021 ACTIVE
Preclinical Assays of Hippocampal-Prefrontal Cortical?Circuit Engagement for Application in Therapeutic Development
Role: Co-Investigator
Funding: NATL INST OF HLTH NIMH
Aug 2021 ACTIVE
Effects of cannabis on age-related cognitive decline and Alzheimers disease pathology
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jul 2021 – Jul 2021
Optogenetic Modulation of Mesocorticolimbic Brain Networks as a Treatment for Parkinsons Disease Cognitive Dysfunction
Role: Other
Funding: AMER ACAD OF NEUROLOGY
May 2021 ACTIVE
Effects of cannabis on Alzheimers disease-related pathology and cognitive decline
Role: Principal Investigator
Funding: FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER
May 2021 ACTIVE
Cognitive and Affective Network Dysfunction and Neuromodulation in Aging and Synucleinopathy
Role: Other
Funding: NATL INST OF HLTH NIA
May 2021 ACTIVE
Mechanisms and therapeutic potential of vagus nerve stimulation in aging and Alzheimers disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2020 ACTIVE
Opioid and cannabinoid interactions in pain and reward
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2020 ACTIVE
Identifying patterns of human polysubstance use to guide development of rodent models
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2020 ACTIVE
Mechanisms of neurodevelopmental effects of parental exposure to commonly used general anesthetic agents
Role: Co-Investigator
Funding: NATL INST OF HLTH NICHD
Jan 2020 – Jun 2021
Modulation of Synuclein Pathology Through Induction of Gamma Band Oscillations in a Mouse Model of DLB
Role: Other
Funding: UF FOUNDATION
Jul 2019 ACTIVE
Novel neuromodulation of motivated and addictive behaviors
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Jun 2019 ACTIVE
Opioid and cannabinoid interactions in pain and reward
Role: Co-Investigator
Funding: UF RESEARCH
Jun 2019 – May 2021
DRPD-ROF2019: A Microfluidics Optrode: A Next Generation Approach to Brain Network Modulation in Parkinsons Disease
Role: Principal Investigator
Funding: UF RESEARCH
Sep 2018 – Aug 2020
Identifying patterns of human polysubstance use to guidedevelopment of rodent models
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2018 ACTIVE
Decision making and basolateral amygdala dysfunction in aging
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2018 – Aug 2020
Hippocampal and dopaminergic?mechanisms of novelty detection underlying cognitive resilience in aging
Role: Other
Funding: NATL INST OF HLTH NIA
Sep 2017 – Aug 2021
Critical Mechanisms Underlying THC Neurotoxicity in Developing CNS
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
May 2017 – Jul 2019
Neural circuits and mechanisms underlying maladaptive risk-taking following cocaine self-administration
Role: Other
Funding: NATL INST OF HLTH NIDA
Jan 2017 – Mar 2021
Cognitive Augmentation through Neuroplasticity (CAN)
Role: Co-Investigator
Funding: US DEPT OF DEFENSE DARPA
Jun 2016 – May 2018
Dissecting interneuron function in addiction using optogenetics
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Sep 2015 – Aug 2020
Role of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis and gamma-aminobutyric acid type A receptor (GABAAR)-mediated excitation in the developmental central and systemic effects of neonatal anesthesia.
Role: Project Manager
Funding: NATL INST OF HLTH NINDS
Jul 2015 – Jun 2018
Lasting behavioral and neuroimaging consequences of adolescent exposure to cannabis smoke
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Apr 2015 – Jan 2021
Risk taking and cocaine use: interactions, mechanisms, and therapeutic targets
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Apr 2015 – Mar 2018
Imaging In Vivo Neural Mechanisms of Synthetic Cathinones (Bath Salts)
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Mar 2015 – Feb 2017
Risk-taking and the nucleus accumbens: neural circultry and the impact of cocaine
Role: Principal Investigator
Funding: UF FOUNDATION via THOMAS H MAREN FOU
Feb 2015 – Mar 2019
Development of a rat model of cannabis smoke self-administration
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
May 2014 – Mar 2020
Neural Mechanisms of Cognitive Decline in Aging
Role: Project Manager
Funding: NATL INST OF HLTH NIA

Education

Fellowship: Psychological and Brain Sciences
1998-2002 · Johns Hopkins University
PhD, Biological Sciences
1998 · University of California, Irvine
BA, Psychology
1994 · Yale University

Contact Details

Phones:
Business:
(352) 294-5203
Emails:
Business:
setlow@ufl.edu
Addresses:
Business Mailing:
PO Box 100256
GAINESVILLE FL 32610