Eric S Porges, Ph.D.
Assistant Professor
Department:
Department of Clinical and Health Psychology
Business Phone:
(352) 294-5838
Business Email:
eporges@ufl.edu
Accomplishments
CTSA Institutional K Scholar
2016
·
University of Florida
Institutional K Scholar
2016
·
CTSA – University of Florida
KL2 awardee
2016
·
Clinical and Translational Science Institute (CTSI, University of Florida
Norman Henry Anderson Award
2012
·
Department of Psychology at the University of Chicago
Teaching Profile
Courses Taught
2019-2023
CLP7979 Advanced Research
2019-2023
CLP7980 Research for Doctoral Dissertation
2018-2023
CLP6971 Research for Master’s Thesis
2017-2020,2022
PSB4934 Special Topics in Physiological Psychology
2017-2019,2021-2022
CLP3911 Introduction to Clinical Research
2017,2019-2022,2022-2023
CLP6940 Supervised Teaching
2016
GMS6893 Clinical and Translational Science Seminar Series
2021-2023
PSB4343C Laboratory in Cognitive Neuroscience
2022
CLP6905 Individual Work
2023
PHC7918 Independent Study
Research Profile
My program of research focuses on age-related changes in cognition and the neurophysiological processes that underlie these changes. In service of this focus, I conduct research that integrates factors known to accelerate aging, including heavy alcohol use and HIV. To explore the relationship between cognition and the brain during aging, my research utilizes neuroimaging (i.e., magnetic resonance spectroscopy (MRS)) and neuromodulation (i.e., non-invasive transcutaneous vagus nerve stimulation (tVNS)).
Open Researcher and Contributor ID (ORCID)
0000-0003-3885-5859
Publications
2022
Cingulo-opercular and frontoparietal control network connectivity and executive functioning in older adults.
GeroScience.
44(2):847-866
[DOI] 10.1007/s11357-021-00503-1.
[PMID] 34950997.
2022
Evaluating the neuropeptide–social cognition link in ageing: the mediating role of basic cognitive skills
Philosophical Transactions of the Royal Society B: Biological Sciences.
377(1858)
[DOI] 10.1098/rstb.2021.0048.
[PMID] 35858076.
2022
Functional Neural Correlates of a Useful Field of View (UFOV)-Based fMRI Task in Older Adults.
Cerebral cortex (New York, N.Y. : 1991).
32(9):1993-2012
[DOI] 10.1093/cercor/bhab332.
[PMID] 34541604.
2022
Higher-order resting state network association with the useful field of view task in older adults.
GeroScience.
44(1):131-145
[DOI] 10.1007/s11357-021-00441-y.
[PMID] 34431043.
2022
The macromolecular MR spectrum does not change with healthy aging.
Magnetic resonance in medicine.
87(4):1711-1719
[DOI] 10.1002/mrm.29093.
[PMID] 34841564.
2022
Validity of the NIH toolbox cognitive battery in a healthy oldest-old 85+ sample.
Journal of the International Neuropsychological Society : JINS.
1-10
[DOI] 10.1017/S1355617722000443.
[PMID] 36239453.
2021
A transcutaneous vagus nerve stimulation study on verbal order memory
Journal of Neurolinguistics.
59
[DOI] 10.1016/j.jneuroling.2021.100990.
2021
Additional considerations for studying brain metabolite levels across pain conditions using proton magnetic resonance spectroscopy
NeuroImage.
224
[DOI] 10.1016/j.neuroimage.2020.117392.
2021
Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV
JAMA Network Open.
4(1)
[DOI] 10.1001/jamanetworkopen.2020.31190.
[PMID] 33449093.
2021
Associations of alcohol use, HIV infection, and age with brain white matter microstructure
Journal of neurovirology.
2021
Author response: The trajectory of cortical GABA across the lifespan, an individual participant data meta-analysis of edited MRS studies
.
[DOI] 10.7554/elife.62575.sa2.
2021
Brain gamma-aminobutyric acid, but not glutamine and glutamate levels are lower in older adults with chronic musculoskeletal pain: considerations by sex and brain location.
Pain reports.
6(3)
[DOI] 10.1097/PR9.0000000000000952.
[PMID] 34514275.
2021
Cerebral Metabolite Concentrations Are Associated With Cortical and Subcortical Volumes and Cognition in Older Adults
Frontiers in Aging Neuroscience.
12
[DOI] 10.3389/fnagi.2020.587104.
[PMID] 33613261.
2021
Change in marijuana use and its associated factors among persons living with HIV (PLWH) during the COVID-19 pandemic: Findings from a prospective cohort.
Drug and alcohol dependence.
225
[DOI] 10.1016/j.drugalcdep.2021.108770.
[PMID] 34049094.
2021
Chronic oxytocin administration in older men modulates functional connectivity during animacy perception
Aging Brain.
1
2021
Circulating Cytokines Predict 1H-Proton MRS Cerebral Metabolites in Healthy Older Adults.
Frontiers in aging neuroscience.
13
[DOI] 10.3389/fnagi.2021.690923.
[PMID] 34489672.
2021
Dedifferentiation of Functional Brain Activation Associated With Greater Visual Discrimination Accuracy in Middle-Aged and Older Adults.
Frontiers in aging neuroscience.
13
[DOI] 10.3389/fnagi.2021.651284.
[PMID] 34366822.
2021
Frequency drift in MR spectroscopy at 3T.
NeuroImage.
241
[DOI] 10.1016/j.neuroimage.2021.118430.
[PMID] 34314848.
2021
Frontal White Matter Hyperintensities and Executive Functioning Performance in Older Adults.
Frontiers in aging neuroscience.
13
[DOI] 10.3389/fnagi.2021.672535.
[PMID] 34262445.
2021
Hyperarousal symptoms and decreased right hemispheric frontolimbic white matter integrity predict poorer sleep quality in combat-exposed veterans.
Brain injury.
35(8):922-933
[DOI] 10.1080/02699052.2021.1927186.
[PMID] 34053386.
2021
Impact of Transcranial Direct Current Stimulation and Cognitive Training on Frontal Lobe Neurotransmitter Concentrations.
Frontiers in aging neuroscience.
13
[DOI] 10.3389/fnagi.2021.761348.
[PMID] 34744698.
2021
Neuroimaging and Cognitive Evidence for Combined HIV‐Alcohol Effects on the Central Nervous System: A Review
Alcoholism: Clinical and Experimental Research.
45(2):290-306
[DOI] 10.1111/acer.14530.
[PMID] 33296091.
2021
Pain and the Montreal Cognitive Assessment (MoCA) in Aging
Pain Medicine.
22(8):1776-1783
[DOI] 10.1093/pm/pnab003.
[PMID] 33718961.
2021
Reduced working memory is associated with heavier alcohol consumption history, role impairment and executive function difficulties
AIDS and behavior.
2021
Relationships between music and empathic decision making in healthy young adults
Music & Science.
2021
Resting-state functional connectivity patterns are associated with worst pain duration in community-dwelling older adults.
Pain reports.
6(4)
[DOI] 10.1097/PR9.0000000000000978.
[PMID] 34901680.
2021
Subjective Cognitive Complaints: Predictors and Health Outcomes in People Living with HIV
AIDS and behavior.
2021
The neurobiology of wellness: H-1-MRS correlates of agency, flexibility and neuroaffective reserves in healthy young adults
NeuroImage.
225
[DOI] 10.1016/j.neuroimage.2020.117509.
[PMID] 33127477.
2021
The trajectory of cortical GABA across the lifespan, an individual participant data meta-analysis of edited MRS studies
eLife.
10
[DOI] 10.7554/elife.62575.
2021
Wrist-worn alcohol biosensors: Applications and usability in behavioral research.
Alcohol (Fayetteville, N.Y.).
92:25-34
[DOI] 10.1016/j.alcohol.2021.01.007.
[PMID] 33609635.
2020
<p>Cortical Thickness Mediates the Association Between Self-Reported Pain and Sleep Quality in Community-Dwelling Older Adults</p>
Journal of Pain Research.
Volume 13:2389-2400
[DOI] 10.2147/jpr.s260611.
2020
An fMRI study of age-associated changes in basic visual discrimination
Brain Imaging and Behavior.
2020
Contributions of Hippocampal Volume to Cognition in Healthy Older Adults
Frontiers in Aging Neuroscience.
12
[DOI] 10.3389/fnagi.2020.593833.
[PMID] 33250765.
2020
History of Alcohol Consumption and HIV Status Related to Functional Connectivity Differences in the Brain During Working Memory Performance
Current HIV Research.
18(3):181-193
[DOI] 10.2174/1570162×18666200217100123.
2020
Independent Contributions of Dorsolateral Prefrontal Structure and Function to Working Memory in Healthy Older Adults
Cerebral cortex (New York, N.Y. : 1991).
31(3):1732-1743
[DOI] 10.1093/cercor/bhaa322.
[PMID] 33188384.
2020
MicroRNA predicts cognitive performance in healthy older adults.
Neurobiology of aging.
95:186-194
[DOI] 10.1016/j.neurobiolaging.2020.07.023.
[PMID] 32846274.
2020
Simultaneous edited MRS of GABA, glutathione, and ethanol
NMR in Biomedicine.
33(4)
[DOI] 10.1002/nbm.4227.
[PMID] 31943424.
2020
Structural Neural Correlates of Double Decision Performance in Older Adults.
Frontiers in aging neuroscience.
12
[DOI] 10.3389/fnagi.2020.00278.
[PMID] 33117145.
2020
The association of white matter free water with cognition in older adults.
NeuroImage.
219
[DOI] 10.1016/j.neuroimage.2020.117040.
[PMID] 32534124.
2020
The Role of Resting-State Network Functional Connectivity in Cognitive Aging
Frontiers in Aging Neuroscience.
12
[DOI] 10.3389/fnagi.2020.00177.
[PMID] 32595490.
2019
Beta-adrenergic antagonism alters functional connectivity during associative processing in a preliminary study of individuals with and without autism
Autism.
24(3):1362361319868633-801
[DOI] 10.1177/1362361319868633.
[PMID] 31416333.
2019
A perspective on objective measurement of the perceived challenge of walking
Frontiers in Human Neuroscience.
13(161)
2019
Associations between subclinical depressive symptoms and reduced brain volume in middle-aged to older adults
Aging & Mental Health.
819-830
[DOI] 10.1080/13607863.2018.1432030.
[PMID] 29381390.
2019
Associations between subclinical depressive symptoms and reduced brain volume in middle-aged to older adults
Aging & Mental Health.
23(7):819-830
[DOI] 10.1080/13607863.2018.1432030.
[PMID] 29381390.
2019
Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites.
NeuroImage.
191:537-548
[DOI] 10.1016/j.neuroimage.2019.02.059.
[PMID] 30840905.
2019
Chronic pain is associated with a brain aging biomarker in community-dwelling older adults
Pain.
160(5):1119-1130
[DOI] 10.1097/j.pain.0000000000001491.
[PMID] 31009418.
2019
Comparison of multi-vendor, single-voxel MR spectroscopy data acquired in healthy brain at 26 sites
Radiology.
2019
Cytokine-associated fatigue prior to, during, and post-chemotherapy for breast cancer.
Journal of neuroimmunology.
334
[DOI] 10.1016/j.jneuroim.2019.577001.
[PMID] 31260949.
2019
Effects of transcranial direct current stimulation paired with cognitive training on functional connectivity of the working memory network in older adults
Frontiers in Aging Neuroscience.
2019
Neurocognitive deficits in a cohort with class 2 and class 3 obesity: Contributions of type 2 diabetes and other comorbidities
Obesity.
2019
Oxytocin alters patterns of brain activity and amygdalar connectivity by age during dynamic facial emotion identification.
Neurobiology of aging.
78:42-51
[DOI] 10.1016/j.neurobiolaging.2019.01.016.
[PMID] 30870779.
2018
Depressive Symptom Dimensions and Their Association with Hippocampal and Entorhinal Cortex Volumes in Community Dwelling Older Adults.
Frontiers in aging neuroscience.
10
[DOI] 10.3389/fnagi.2018.00040.
[PMID] 29515435.
2018
Discrepancies Between Crystallized and Fluid Ability Are Associated With Frequency of Social and Physical Engagement in Community Dwelling Older Adults
Journal of Clinical and Experimental Neuropsychology.
40(10):963-970
[DOI] 10.1080/13803395.2018.1452195.
2018
Educational Attainment Moderates the Association Between Hippocampal Volumes and Memory Performances in Healthy Older Adults
Frontiers in Aging Neuroscience.
10
[DOI] 10.3389/fnagi.2018.00361.
[PMID] 30467475.
2018
Heavy Alcohol Use and Age Effects on HIV‐Associated Neurocognitive Function
Alcoholism: Clinical and Experimental Research.
[DOI] 10.1111/acer.13915.
[PMID] 30371953.
2018
Mobility function and recovery after stroke: preliminary insights from sympathetic nervous system activity
.
42:224-232
2018
Neural Response to Working Memory Demand Predicts Neurocognitive Deficits in HIV
Journal of neurovirology.
24(3):291-304
[DOI] 10.1007/s13365-017-0607-z.
[PMID] 29280107.
2018
Psychostimulant Drug Effects on Glutamate, Glx, and Creatine in the Anterior Cingulate Cortex and Subjective Response in Healthy Humans
Neuropsychopharmacology.
43(7):1498-1509
[DOI] 10.1038/s41386-018-0027-7.
[PMID] 29511334.
2018
Sympathetic nervous system activity measured by skin conductance quantifies the challenge of walking adaptability tasks after stroke
.
60:148-153
2018
The Impact of Alcohol Use on Frontal White Matter in HIV.
Alcoholism, clinical and experimental research.
42(9):1640-1649
[DOI] 10.1111/acer.13823.
[PMID] 29957870.
2018
Wrist-Worn Alcohol Biosensors: Strengths, Limitations, and Future Directions.
Alcohol (Fayetteville, N.Y.).
81:83-92
[DOI] 10.1016/j.alcohol.2018.08.013.
[PMID] 30179709.
2017
14 The Roots of Compassion: An Evolutionary and Neurobiological Perspective
.
173
2017
Association between subclinical depressive symptoms and reduced brain volume in middle-aged to older adults
Aging & Mental Health.
2017
Effects of in-Scanner Bilateral Frontal tDCS on Functional Connectivity of the Working Memory Network in Older Adults
Frontiers in Aging Neuroscience.
11
[DOI] 10.3389/fnagi.2019.00051.
[PMID] 30930766.
2017
Frontal gamma-aminobutyric acid concentrations are associated with cognitive performance in older adults
Biological psychiatry. Cognitive neuroscience and neuroimaging.
2(1):38-44
[DOI] 10.1016/j.bpsc.2016.06.004.
[PMID] 28217759.
2017
Impact of Tissue Correction Strategy on Gaba-Edited Mrs Findings
NeuroImage.
162:249-256
[DOI] 10.1016/j.neuroimage.2017.08.073.
[PMID] 28882635.
2017
Non-Invasive Vagal Nerve Stimulation Effects on Hyperarousal and Autonomic State in Patients With Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury: Preliminary Evidence
Frontiers in Medicine.
4
[DOI] 10.3389/fmed.2017.00124.
[PMID] 28824913.
2017
Precuneus Abnormalities in Middle-Aged to Older Adults With Depressive Symptoms: An Analysis of Bdi-II Symptom Dimensions
Psychiatry Research-Neuroimaging.
268:9-14
[DOI] 10.1016/j.pscychresns.2017.08.002.
[PMID] 28837829.
2016
Age exacerbates HIV-associated white matter abnormalities
Journal of neurovirology.
22(2):201-12
[DOI] 10.1007/s13365-015-0386-3.
[PMID] 26446690.
2016
Cognitive Aging and the Hippocampus in Older Adults.
Frontiers in aging neuroscience.
8
[DOI] 10.3389/fnagi.2016.00298.
[PMID] 28008314.
2016
Cognitively Engaging Activity Is Associated with Greater Cortical and Subcortical Volumes.
Frontiers in aging neuroscience.
8
[DOI] 10.3389/fnagi.2016.00094.
[PMID] 27199740.
2016
Current Heavy Alcohol Consumption is Associated with Greater Cognitive Impairment in Older Adults.
Alcoholism, clinical and experimental research.
40(11):2435-2444
[DOI] 10.1111/acer.13211.
[PMID] 27658235.
2016
Edgewise and Subgraph-Level Tests for Brain Networks
Statistics in Medicine.
35(27):4994-5008
[DOI] 10.1002/sim.7039.
[PMID] 27397632.
2016
Effects of Propranolol on Conversational Reciprocity in Autism Spectrum Disorder: a Pilot, Double-Blind, Single-Dose Psychopharmacological Challenge Study
Psychopharmacology.
233(7):1171-1178
[DOI] 10.1007/s00213-015-4199-0.
[PMID] 26762378.
2016
Frontal Structural Neural Correlates of Working Memory Performance in Older Adults.
Frontiers in aging neuroscience.
8
[DOI] 10.3389/fnagi.2016.00328.
[PMID] 28101053.
2016
Oxytocin’s effect on resting-state functional connectivity varies by age and sex.
Psychoneuroendocrinology.
69:50-9
[DOI] 10.1016/j.psyneuen.2016.03.013.
[PMID] 27032063.
2015
Amygdala subnuclei connectivity in response to violence reveals unique influences of individual differences in psychopathic traits in a nonforensic sample
Human brain mapping.
36(4):1417-1428
[DOI] 10.1002/hbm.22712.
[PMID] 25557777.
2015
Cognitive-motor dysfunction after severe traumatic brain injury: A cerebral interhemispheric disconnection syndrome.
Journal of clinical and experimental neuropsychology.
37(10):1062-73
[DOI] 10.1080/13803395.2015.1077930.
[PMID] 26340588.
2015
Individual differences in vagal regulation are related to testosterone responses to observed violence
Frontiers in Psychology.
6
[DOI] 10.3389/fpsyg.2015.00019.
[PMID] 25759673.
2014
Maladaptive autonomic regulation in PTSD accelerates physiological aging.
Frontiers in psychology.
5
[DOI] 10.3389/fpsyg.2014.01571.
[PMID] 25653631.
2014
Oxytocin receptor gene variation predicts empathic concern and autonomic arousal while perceiving harm to others
Social Neuroscience.
9(1):1-9
[DOI] 10.1080/17470919.2013.863223.
[PMID] 24295535.
2014
Utilization of Central Nervous System Resources for Preparation and Performance of Complex Walking Tasks in Older Adults
Frontiers in Aging Neuroscience.
6
[DOI] 10.3389/fnagi.2014.00217.
[PMID] 25202270.
2013
A possible mechanism for PTSD symptoms in patients with traumatic brain injury: central autonomic network disruption
.
2013
Violence as a source of pleasure or displeasure is associated with specific functional connectivity with the nucleus accumbens.
Frontiers in human neuroscience.
7
[DOI] 10.3389/fnhum.2013.00447.
[PMID] 23964226.
2011
Imagining being the agent of actions that carry different moral consequences: an fMRI study
Neuropsychologia.
49(11):2994-3001
[DOI] 10.1016/j.neuropsychologia.2011.06.024.
[PMID] 21762712.
2011
Parenthood, stress, and the brain.
Biological psychiatry.
70(9):804-5
[DOI] 10.1016/j.biopsych.2011.09.003.
[PMID] 21986092.
2008
Perspective taking is associated with specific facial responses during empathy for pain.
Brain research.
1227:153-61
[DOI] 10.1016/j.brainres.2008.06.066.
[PMID] 18619426.
Larger and more dentated hippocampal structure is associated with better memory in the oldest-old
.
[DOI] 10.1101/2022.04.10.487750.
Network Segregation Predicts Processing Speed in the Cognitively Healthy Oldest-old
.
[DOI] 10.1101/2021.10.05.463207.
The trajectory of cortical GABA levels across the lifespan: An individual participant data meta-analysis of edited MRS studies
.
[DOI] 10.1101/2020.07.23.218792.
Grants
Sep 2021
ACTIVE
Simultaneous Hadamard Editing of GABA and Glutathione
Role: Principal Investigator
Funding: JOHNS HOPKINS UNIVERSITY
via NATL INST OF HLTH NIBIB
Sep 2021
ACTIVE
Interventions to improve alcohol-related comorbidities along the gut-brain axis in persons with HIV infection
Role: Other
Funding: NATL INST OF HLTH NIAAA
Sep 2021
ACTIVE
Pairing tVNS and exposure and response prevention to improve symptoms of OCD
Role: Co-Investigator
Funding: INTL OCD FOUNDATION
Sep 2020
– Dec 2021
Cortical Inhibition and Mobility in Older Adults
Role: Other
Funding: NATL INST OF HLTH NIA
Aug 2020
ACTIVE
Understanding pancreatic endocrine and exocrine loss in pre-type 1 diabetes
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Jul 2020
– May 2021
Addressing alcohol misuse in HIV prevention and care: The Brown University Alcohol Research Center on HIV
Role: Other
Funding: BROWN UNIV
via NATL INST OF HLTH NIAAA
Aug 2017
ACTIVE
Cognitive and functional deficits associated with reduced cortical GABA in HIV-infected heavy drinkers
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAAA
Apr 2017
– Mar 2018
Together: Transforming and Translating Discovery to Improve Health
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Sep 2016
ACTIVE
Effects of experimentally-induced reductions in alcohol consumption on brain cognitive, and clinical outcomes and motivation for changing drinking in older persons with HIV infection
Role: Other
Funding: NATL INST OF HLTH NIAAA
Apr 2016
– Mar 2017
TOGETHER: TRANSFORMING AND TRANSLATING DISCOVERY TO IMPROVE ,HEALTH ,
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Jul 2014
– Jun 2022
Age associated changes in attention and arousal (Attentive Brain Study)
Role: Principal Investigator
Funding: UF FOUNDATION
Education
Post-Doctoral Fellow
2013-2016
·
University of Florida
Ph.D. Integrative Neuroscience
2013
·
University of Chicago, Chicago, IL
B.A. Cognitive Science
2004
·
Hampshire College, Amherst, MA
Contact Details
Phones:
- Business:
- (352) 294-5838
Emails:
- Business:
- eporges@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100165
GAINESVILLE FL 32610 - Business Street:
-
RM 3117
2004 MOWRY RD
GAINESVILLE FL 32601