Kyle D Allen

Kyle D Allen,

ASO CHAIR & ASO PROF

Department: EG-BIOMEDICAL ENGINEERING
Business Phone: (352) 273-9337
Business Email: kyle.allen@bme.ufl.edu

Teaching Profile

Courses Taught
2013-2015,2017-2021,2019-2021
BME5703 Statistical Methods for Biomedical Engineering
2016-2019
EGN4912 Engineering Directed Independent Research
2019
BME6010 Clinical Immersion
2016-2019
BME7980 Research for Doctoral Dissertation
2016-2019
BME7979 Advanced Research
2019
BME6018 Clinical Correlations in BME
2019
EGN6913 Engineering Graduate Research
2018
ANG7980 Research for Doctoral Dissertation
2018
ANG7979 Advanced Research
2017-2018
BME6940 Supervised Teaching
2018
BME3012 Clinically-Inspired Engineering Design
2014-2017,2021
BME4931 Special Topics in Biomedical Engineering
2016-2017
BME6907 BME Project
2016
BME6938 Special Topics in Biomedical Engineering
2012-2013
BME6936 Biomed Engr Seminar
2012-2013
BME1008 Introduction to Biomedical Engineering

Publications

2022
A Novel Device for the Quantification of Synovial Fluid Viscosity Via Magnetic Deflection.
Journal of biomechanical engineering. 144(8) [DOI] 10.1115/1.4053794. [PMID] 35147159.
2022
Age alters gait compensations following meniscal injury in male rats.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. [DOI] 10.1002/jor.25306. [PMID] 35285977.
2022
Autonomic Nervous System Dysregulation and Osteoarthritis Pain: Mechanisms, Measurement, and Future Outlook.
Current rheumatology reports. [DOI] 10.1007/s11926-022-01071-9. [PMID] 35420372.
2022
Measures of cardiovascular function suggest autonomic nervous system dysregulation after surgical induction of joint injury in the male Lewis rat.
Osteoarthritis and cartilage. 30(4):586-595 [DOI] 10.1016/j.joca.2021.12.008. [PMID] 35017058.
2021
Chronic Pain is Associated With Reduced Sympathetic Nervous System Reactivity During Simple and Complex Walking Tasks: Potential Cerebral Mechanisms.
Chronic stress (Thousand Oaks, Calif.). 5 [DOI] 10.1177/24705470211030273. [PMID] 34286166.
2021
Fast nanoparticle rotational and translational diffusion in synovial fluid and hyaluronic acid solutions.
Science advances. 7(27) [DOI] 10.1126/sciadv.abf8467. [PMID] 34193423.
2021
Innovation-Oriented Medical School Curricula: Review of the Literature.
Cureus. 13(10) [DOI] 10.7759/cureus.18498. [PMID] 34754659.
2021
Partial high frequency nerve block decreases neuropathic signaling following chronic sciatic nerve constriction injury.
Journal of neural engineering. 18(2) [DOI] 10.1088/1741-2552/abbf03. [PMID] 33027782.
2020
Characterization of Post-Traumatic Osteoarthritis in Rats Following Anterior Cruciate Ligament Rupture by Non-Invasive Knee Injury (NIKI).
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 38(2):356-367 [DOI] 10.1002/jor.24470. [PMID] 31520482.
2020
Factors affecting the reliability of behavioral assessments for rodent osteoarthritis models.
Laboratory animals. 54(4):317-329 [DOI] 10.1177/0023677219867715. [PMID] 31431137.
2020
The clearance and biodistribution of magnetic composite nanoparticles in healthy and osteoarthritic rat knees.
Journal of controlled release : official journal of the Controlled Release Society. 321:259-271 [DOI] 10.1016/j.jconrel.2020.01.052. [PMID] 32004585.
2020
The effects of age on the severity of joint damage and intra-articular inflammation following a simulated medial meniscus injury in 3, 6, and 9 month old male rats.
Connective tissue research. 61(1):82-94 [DOI] 10.1080/03008207.2019.1641495. [PMID] 31438735.
2020
Use of magnetic capture to identify elevated levels of CCL2 following intra-articular injection of monoiodoacetate in rats.
Connective tissue research. 61(5):485-497 [DOI] 10.1080/03008207.2019.1620223. [PMID] 31438731.
2019
Automated Gait Analysis Detects Improvements after Intracellular σ Peptide Administration in a Rat Hemisection Model of Spinal Cord Injury.
Annals of biomedical engineering. 47(3):744-753 [DOI] 10.1007/s10439-019-02198-0. [PMID] 30627839.
2019
Fully automatic knee osteoarthritis severity grading using deep neural networks with a novel ordinal loss.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 75:84-92 [DOI] 10.1016/j.compmedimag.2019.06.002. [PMID] 31238184.
2019
Functional Measures of Grip Strength and Gait Remain Altered Long-term in a Rat Model of Post-traumatic Elbow Contracture.
Journal of biomechanical engineering. [DOI] 10.1115/1.4043433. [PMID] 30958506.
2018
Behavioral characteristics of capsaicin mediated cutaneous, myogenic, and arthrogenic orofacial nociception in rats.
Archives of oral biology. 92:18-24 [DOI] 10.1016/j.archoralbio.2018.04.013. [PMID] 29738922.
2018
Quadrupedal rodent gait compensations in a low dose monoiodoacetate model of osteoarthritis.
Gait & posture. 63:73-79 [DOI] 10.1016/j.gaitpost.2018.04.023. [PMID] 29723651.
2018
The effect of Mg-Ca-Sr alloy degradation products on human mesenchymal stem cells.
Journal of biomedical materials research. Part B, Applied biomaterials. 106(2):697-704 [DOI] 10.1002/jbm.b.33869. [PMID] 28323384.
2018
The Open Source GAITOR Suite for Rodent Gait Analysis.
Scientific reports. 8(1) [DOI] 10.1038/s41598-018-28134-1. [PMID] 29955094.
2017
Automated Gait Analysis Through Hues and Areas (AGATHA): A Method to Characterize the Spatiotemporal Pattern of Rat Gait.
Annals of biomedical engineering. 45(3):711-725 [DOI] 10.1007/s10439-016-1717-0. [PMID] 27554674.
2017
Magnetic particle translation as a surrogate measure for synovial fluid mechanics.
Journal of biomechanics. 60:9-14 [DOI] 10.1016/j.jbiomech.2017.05.015. [PMID] 28583675.
2017
Quantitative histological grading methods to assess subchondral bone and synovium changes subsequent to medial meniscus transection in the rat.
Connective tissue research. 58(3-4):373-385 [DOI] 10.1080/03008207.2016.1251425. [PMID] 27797605.
2017
Special Issue: Spotlight on the Future of Musculoskeletal Biomechanics: Frontiers and Challenges in Musculoskeletal Biomechanics.
Journal of biomechanical engineering. 139(11) [DOI] 10.1115/1.4038049. [PMID] 28973131.
2016
Investigation of the Capture of Magnetic Particles From High-Viscosity Fluids Using Permanent Magnets.
IEEE transactions on bio-medical engineering. 63(2):372-8 [DOI] 10.1109/TBME.2015.2458783. [PMID] 26208261.
2016
Magnetic Capture of a Molecular Biomarker from Synovial Fluid in a Rat Model of Knee Osteoarthritis.
Annals of biomedical engineering. 44(4):1159-69 [DOI] 10.1007/s10439-015-1371-y. [PMID] 26136062.
2016
Mechanical Integrity of a Decellularized and Laser Drilled Medial Meniscus.
Journal of biomechanical engineering. 138(3) [DOI] 10.1115/1.4032381. [PMID] 26720513.
2016
Peri-implant tissue response and biodegradation performance of a Mg-1.0Ca-0.5Sr alloy in rat tibia.
Materials science & engineering. C, Materials for biological applications. 62:79-85 [DOI] 10.1016/j.msec.2015.12.002. [PMID] 26952400.
2015
A novel operant-based behavioral assay of mechanical allodynia in the orofacial region of rats.
Journal of neuroscience methods. 248:1-6 [DOI] 10.1016/j.jneumeth.2015.03.022. [PMID] 25823368.
2015
Comparing the mechanical properties of the porcine knee meniscus when hydrated in saline versus synovial fluid.
Journal of biomechanics. 48(16):4333-8 [DOI] 10.1016/j.jbiomech.2015.10.046. [PMID] 26592438.
2015
Spatiotemporal gait compensations following medial collateral ligament and medial meniscus injury in the rat: correlating gait patterns to joint damage.
Arthritis research & therapy. 17 [DOI] 10.1186/s13075-015-0791-2. [PMID] 26462474.
2014
Gait analysis methods for rodent models of osteoarthritis.
Current pain and headache reports. 18(10) [DOI] 10.1007/s11916-014-0456-x. [PMID] 25160712.
2012
Changes in midbrain pain receptor expression, gait and behavioral sensitivity in a rat model of radiculopathy.
The open orthopaedics journal. 6:383-91 [DOI] 10.2174/1874325001206010383. [PMID] 22962568.
2012
Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis.
Arthritis research & therapy. 14(2) [DOI] 10.1186/ar3801. [PMID] 22510443.
2011
Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 29(5):694-703 [DOI] 10.1002/jor.21309. [PMID] 21437948.
2011
Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 29(1):1-7 [DOI] 10.1002/jor.21206. [PMID] 20665551.
2011
Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism.
Arthritis research & therapy. 13(4) [DOI] 10.1186/ar3451. [PMID] 21871102.
2010
Evaluating intra-articular drug delivery for the treatment of osteoarthritis in a rat model.
Tissue engineering. Part B, Reviews. 16(1):81-92 [DOI] 10.1089/ten.teb.2009.0447. [PMID] 19943805.
2009
Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen.
Arthritis and rheumatism. 60(9):2684-93 [DOI] 10.1002/art.24783. [PMID] 19714629.
2009
Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy.
Spine. 34(7):648-54 [DOI] 10.1097/BRS.0b013e318197f013. [PMID] 19333095.
2008
Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen.
Arthritis and rheumatism. 58(1):164-71 [DOI] 10.1002/art.23231. [PMID] 18163498.
2008
The effects of protein-coated surfaces on passaged porcine TMJ disc cells.
Archives of oral biology. 53(1):53-9 [PMID] 17825784.
2007
Effect of passage and topography on gene expression of temporomandibular joint disc cells.
Tissue engineering. 13(1):101-10 [PMID] 17518584.
2006
Tissue Engineering of the TMJ disc: a review.
Tissue engineering. 12(5):1183-96 [PMID] 16771633.
2006
Viscoelastic characterization of the porcine temporomandibular joint disc under unconfined compression.
Journal of biomechanics. 39(2):312-22 [PMID] 16321633.
2005
A surface-regional and freeze-thaw characterization of the porcine temporomandibular joint disc.
Annals of biomedical engineering. 33(7):951-62 [PMID] 16060536.

Grants

Apr 2022 ACTIVE
Treatment of Knee Osteoarthritis via Intra-articular Delivery of an Immunosuppressive Enzyme
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Aug 2020 ACTIVE
Investigating the role of osteoarthritic pain and inflammation in autonomic nervous system shifts using preclinical models
Role: Other
Funding: NATL INST OF HLTH NIAMS
Sep 2019 ACTIVE
Planning Grant: Engineering Research Center for Neural Engineering Systems with Societal Impact (NESSI)
Role: Co-Investigator
Funding: NATL SCIENCE FOU
Jul 2018 – Dec 2020
Controlling the Phenotype of Synovial Macrophages: A novel strategy to modify the pathogenesis and symptoms of post-traumatic osteoarthritis
Role: Co-Investigator
Funding: US ARMY MED RES ACQUISITION
Apr 2018 ACTIVE
Nanoparticle targeting within the joint for site-specific delivery of osteoarthritis therapeutics
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Mar 2018 ACTIVE
OA Pathogenesis beyond Cartilage: A preclinical study of the sources of OA pain
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Aug 2016 – Aug 2018
Support for Swati Khare
Role: Principal Investigator
Funding: ST JOSEPH'S HOSP MED CNT BARROW NEURO
Jul 2015 – May 2021
Magnetic Capture of Osteoarthritis Biomarkers
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Jul 2006 – Dec 2020
21st Century Research & Economic Development Investment Program (REDIP)
Role: Project Manager
Funding: STATE UNIV SYS OF FL BOARD OF GOVERNORS

Contact Details

Phones:
Business:
(352) 273-9337
Emails:
Addresses:
Business Mailing:
P O BOX 116131
GAINESVILLE FL 326110001